Hydroshear Plus DNA Shearing


The Best Way to Fragment DNA for Genomic and Paired End Library Construction, High Throughput & Long Reads Sequencing!

Ideal for uniform and reproducible making of large DNA fragments for long reads with Next- and Third-Generation Sequencers!!  

Digilab HydroShear Plus DNA Shearing offers the simplest, most reproducible, and most controllable method available for generating random DNA fragments. This software-driven device uses hydrodynamic shearing forces to fragment DNA strands.

 Hydroshear Plus DNA Shearing, the best way to fragment DNA

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HydroShear Plus

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With Digilab HydroShear Plus DNA Shearing, virtually any source of DNA at any concentration in volumes as small as 40μl can be randomly fractured to within a two-fold size distribution. For instance, if the desired target size is 2kb, the HydroShear Plus can be calibrated to produce a distribution centered on 2kb with 90% of the DNA falling between 1.3kb and 2.6kb – ideal for paired-end library construction. It is the best system for making long DNA fragments for single molecule sequencing.

Digilab HydroShear Plus DNA Shearing Features:

  • Automated multi-port valve to allow hands-free multiple washing
  • Integrated holder for three wash solutions and waste
  • Integrated holder for sample vial
  • Optional netbook with pre-loaded Hydroshear Plus software

 New Publication

- Accurate Shearing of Chromosomal DNA by Dr. Igor Zlatkin

 New Application Note

- Generating large DNA fragments for library construction or sequencing by Dr. Igor Zlatkin
- How to Choose the Proper Shearing Assembly Unit. by Dr. Igor Zlatkin


Optimized Hydroshear wash kit